Patients involved in major trauma frequently suffer from severe blood loss and anemia, which can be challenging to treat. Additional issues are presented in the population of Jehovah's Witness patients, who refuse transfusions of allogenic blood or its components. We established a stable hemodynamic status in a young Jehovah's Witness patient with major trauma by applying principles of patient blood management. About the Patient Blood Management Case Report Series Patient Blood Management (PBM)