The Organic Chemistry of Drug Design and Drug Action

Standard medicinal chemistry courses and textbooks are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This textbook represents a novel and unique approach based on physical organic chemical principles and reaction mechanisms that rationalize drug action and allow the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. The Third Edition reflects significant changes in the drug industry and the process of drug design over...